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RESEARCH

Preface

Endoscopic Research Awards

Application Deadline 5:00 PM CST, Friday, January 30, 2015


 

Submission

The ASGE Research Committee requires electronic submission in a single PDF file. ASGE Membership at the time of submission is a requirement of this award.  If you are experiencing problems submitting your grant application, please email the application and/or questions to grants@asge.org or call Liz O'Keefe at 630.570.5623.

**Please note that grants not meeting the stated requirements, such as exceeding the page limits, will be administratively returned without review**

Description

ASGE Endoscopic Research Awards are offered to investigators (MD, DO, PhD, or equivalent) for projects in basic, translational and clinical research in endoscopy. The ASGE is particularly interested in endoscopic research pertaining to (in no particular order): colorectal cancer, Barrett's esophagus, training/credentialing/simulation, issues specific to under-represented minorities (defined as women and individuals of diverse ethnic/cultural backgrounds), measuring/improving quality and efficiency, endoscope reprocessing and infection control, endoscopy/anesthesia monitoring and preparation, comparative effectiveness, NOTES®, novel endoscopic treatments for obesity, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography (ERCP), and other endoscopically-guided imaging/intervention. The research committee will consider funding "seed" projects if there is an explicit outline for subsequent projects, and their funding plan (e.g. NIH, VA Merit), based on the preliminary data generated by the proposed pilot.

Objective 

To promote research in gastrointestinal endoscopy.

Eligibility 

Candidate is required to be an ASGE member at the time of application, be an MD (or have equivalent degree), and be currently practicing in North America (international applications will be considered as described below). Candidates who are delinquent on prior ASGE research grants (e.g., progress reports) are not eligible for future ASGE funding. If the candidate is a trainee, there must be a letter from the trainee's Division Chief confirming the trainee's ongoing appointment and position title at the institution for the duration of the grant.; if the trainee applicant is not guaranteed an appointment for the duration of the grant, a contingency plan is required.

Awards and Requirements

  1. Grants may be requested for a maximum of $75,000 in total funding, and spanning no more than two years.
  2. Requests for funding pilot studies that will generate needed preliminary data to justify a larger clinical trial, as well as larger requests for definitive studies, will be considered. In order to maximize the funds available for research, budgets may not include indirect costs or travel expenses.
  3. The budget request should be detailed and all items should be clearly related to the research proposal. Budgets will be carefully scrutinized by the ASGE Research Committee and will be considered in the scoring of the grant. Inappropriate or poorly justified budgets will jeopardize the application. Additionally, the research committee retains the right to adjust the award to an amount it feels appropriate for the project or per budget restrictions.
  4. Funding requests may include:
    1. Personnel (e.g., research assistant and/or faculty salary support; this should include a percentage of effort for the proposed study with appropriate justification).
    2. Study supplies
    3. Equipment essential for study
  5. Funding will not be provided for:
    1. Salary support for trainees
    2. Computer purchases (unless a unique application is proposed)
    3. Standard equipment and supplies needed for appropriate patient care (for example, sclerotherapy needles)
    4. Travel to meetings
    5. Indirect cost
  6. Duration of funding: up to two years. The second year of continued funding is contingent on satisfactory study progress determined by the Chair of the Research Committee based on mandatory annual progress reports.
  7. Studies which include more than one center will require institutional review board approval from each center. The participating institutions and investigators should be specified in the application.
  8. Progress reports must be submitted to the Chair of the Research Committee via the ASGE Administrative Offices every 12 months for the duration of the project (ideally in advance of the 1-year mark for 2-year studies so that the second year's funding is not delayed. Progress reports must include a financial statement from the institutional grants or accounting office. Failure to submit a progress report by the stated deadline may affect future funding.
  9. Requests for no-cost extensions must be submitted in writing to the Chair of the Research Committee via the ASGE administrative office. This request should include a) a detailed summary regarding how grant money has been spent (or forecasted to be spent) up to the original award end date, and b) a proposed budget describing in reasonable detail how the remaining funds will be spent in the upcoming year. Although the mentor can be, and should be, involved in this No-Cost Extension and Progress Report, it should not be written by the mentor - it should be drafted by and signed by the mentee PI. Change in PI for the upcoming award period should be proposed by and justified by the original PI, including changes of the PI-ship to the mentor.

Upon completion of the award, ASGE requires that a final scientific and financial report from the grants or account office be submitted. All publications and abstracts must acknowledge support from the ASGE.

Selection Criteria

Grants are awarded based on the scientific merit of the proposal and assessment of the investigator's ability to complete the project (supportive environment, experience, training, availability of patients and other resources needed). The proposed research project must be approved by the ASGE Research Committee and should also be of such quality as to lead to presentation at Digestive Disease Week® and subsequent full publication. One objective of these awards is the eventual submission of larger research funding requests, including federal funding, and proposals with such potential will be given priority.

International Eligibility

ASGE International Members are eligible to apply for an Endoscopic Research Award (Current ASGE membership is a requirement of eligibility for grants and awards). The ASGE Research Committee will consider funding one international project for up to $75,000.  The project justification should explain the relevance of the project to the ASGE membership, and should explain if there are unique reasons why an international location for the project might be more feasible than in North America. All other standards listed above will apply to international applicants. Please contact grants@asge.org or Liz O'Keefe at 630.570.5623 for more information on eligibility.

Review Process

The ASGE Research Committee will review the proposals and recommend awardees. The final selection of awards is made by the ASGE Governing Board.

Deadline

Application Deadline 5:00 PM CST, Friday, January 30, 2015*

The number of awards granted is contingent on funds available.

Grant Proposal Outline

Each application must have page numbers, be in Arial 11 point font, with >0.75" margins, and contain:

1. Abstract - Include name, institution, project title, mentor name if applicable, and a one-page summary of the proposal including hypothesis and goals. Suggested headings include: Background; Aims/Hypothesis; Methods; Analysis and Sample size Calculation; Timeline and Feasibility; Future Study. Limit to one page.


2. Biosketch- Provide NIH-style biosketch for candidate, mentor and co-investigators that includes all relevant publications and current funding (see example at http://grants.nih.gov/grants/funding/phs398/phs398.html). Limit to four pages.

3. Grant Proposal - Prepare according to NIH-form SF 424 (R&R) guidelines. (Excluding References) Limit to five pages and include each of the following headers: 

     a. Title and Introduction

     b. Hypothesis & Specific Aims - This should be a clear statement of the problem, the related hypothesis/question and a brief description of the proposed scientific plan. Provide a concise explanation in a few sentences.

     c. Background and Significance to Endoscopic Practice- Justification regarding scope of the problem, and relevance to ASGE membership and the endoscopy community.

     d. Innovation

     e. Preliminary Data - Outline prior studies or your pilot work already completed in this area. If prior studies have not been done by your group, give brief details of pilot work done by others.

     f. Approach - Describe the methods of collection and analysis of the data. A statistical data analysis plan, including sample size calculations, is required, even for retrospective studies. Be as specific as possible. Links to sample size calculators and basic on-line statistical calculators are included below: GraphpadRStatistics Online Computational Resource (SOCR)Rollin Brant's sample size calculator,University of Iowa sample size calculator

     g. Pitfalls, alternatives and future directions

     h. Conflict of Interest - A statement regarding conflict of interest and/or financial ownership, patent rights, etc. of technique/devices being studied in the grant proposal must be included in each grant application, along with a plan for resolution of these conflicts. If conflicts are significant and do not appear to be able to be resolved, the application may be denied.

4. References - Limit to two pages.

5. Budget - Please justify all items (including %effort) with a separate budget justification page. Budgets will be carefully scrutinized by the Research Committee and will be considered in the scoring of the grant. Inappropriate or poorly justified budgets will jeopardize the likelihood of the application receiving an award. Additionally, the committee retains the right to adjust the award to an amount it feels appropriate for the project. Limit to one page for budget, and one additional page for justification.

     a. The maximum request should be $75,000. Grant support for this amount may be spread over two years. The second year of continued funding is contingent on satisfactory progress demonstrated in mandatory yearly progress reports.

     b. The budget request should be detailed and all items should be clearly related to the research proposal.

     c. Funding requests (see "Awards and Requirements" section numbers 3-5).

     d. Submitted projects for additional funding should include a copy of the previous year's budget and Progress Report Form.

6. Resources and Environment - List facilities, equipment, and available personnel required to complete this project. Be aware that reviewers of the grant may not be aware of the resources and/or patient volumes of your center. Letters of collaborations should be included, if applicable, especially if from other institutions. Limit resources statement and collaborator letters to one page each.

7. Institutional Review Board - Attach IRB approval or proof of exempt status, if available (this may help if ability to obtain IRB approval is called into question by the committee). If not available at time of application, and the application is funded, no funds will be released until IRB approval is received by the ASGE Research office.

8. Supporting letters (Required from key collaborators, especially if from other institutions)


 

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