Released on Jan 20, 2023

New Evidence that Colonoscopy Outperforms All Other Screening Tests for Polyp and Cancer Sensitivity

Colonoscopy is currently the only recommended colorectal cancer screening recommended at 10-year intervals, and the only test recommended at longer than 5-year intervals. Colonoscopy effectively prevents colorectal cancer even at 10-year intervals because of its very high sensitivity for precancerous polyps and its unique capacity to both detect and resect polyps in the same setting.  Several previous lines of evidence suggest that high quality colonoscopy provides protection for even longer than 10 years. 

ASGE welcomes this new report from the German screening colonoscopy program providing direct observational evidence that patients undergoing colonoscopy 10 years after an initial negative screening colonoscopy, have a low risk of cancer or important polyps being identified.  These data indicate colonoscopy for some people, especially younger women, could wait longer than 10 years after a negative first screening colonoscopy before having a repeat colonoscopy. These data confirm once again that colonoscopy outperforms all other screening tests for polyp and cancer sensitivity.

ASGE strongly encourages all Americans age 45 and older to ask their doctors to order a colorectal cancer screening test.  While colonoscopy remains the most effective test, stool-based tests with useful sensitivity are available for those who are hesitant or cannot undergo colonoscopy.  Your doctor can help you find a colorectal cancer screening test that is right for you.

About Gastrointestinal Endoscopy
Gastrointestinal endoscopic procedures allow the gastroenterologist to visually inspect the upper gastrointestinal tract (esophagus, stomach and duodenum) and the lower bowel (colon and rectum) through an endoscope, a thin, flexible device with a lighted end and a powerful lens system. Endoscopy has been a major advance in the treatment of gastrointestinal diseases. For example, the use of endoscopes allows the detection of ulcers, cancers, polyps and sites of internal bleeding. Through endoscopy, tissue samples (biopsies) may be obtained, areas of blockage can be opened and active bleeding can be stopped. Polyps in the colon can be removed, which has been shown to prevent colon cancer.

About the American Society for Gastrointestinal Endoscopy
Since its founding in 1941, the American Society for Gastrointestinal Endoscopy (ASGE) has been dedicated to advancing patient care and digestive health by promoting excellence and innovation in gastrointestinal endoscopy. ASGE, with almost 15,000 members worldwide, promotes the highest standards for endoscopic training and practice, fosters endoscopic research, recognizes distinguished contributions to endoscopy, and is the foremost resource for endoscopic education. Visit and for more information and to find a qualified doctor in your area.


American Society for Gastrointestinal Endoscopy
3300 Woodcreek Drive Downers Grove, IL 60515
P (630) 573-0600
F (630) 963-8332

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Andrea Lee
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