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Background and Aims: An L-menthol preparation (Minclea®) (hereinafter referred to as “PO”) is used as an anti-peristaltic drug. This effect not only suppresses peristalsis but also relaxes the muscle. In the present study, we examined the impact of PO on the ability to observe the stomach on transnasal endoscopy.
[Subjects] Fifty-four patients with atrophic gastritis were sprayed with PO during routine examination with transnasal endoscopy. Their mean age was 62.1 years, and the male/female ratio was 32/22. The degree of atrophy (Kimura-Takemoto classification) was mild (C-1, C-2) in 14, moderate (C-3, O-1) in 17, and severe (O-2, O-3) in 23. Subjective symptoms were none or mild.
PO was sprayed into the pyloric antrum during peristalsis, and into the lower greater curvature of stomach when no peristalsis occurred. Extension of the gastric corpus, interval of folds in the greater curvature, and peristalsis in the pyloric antrum were compared retrospectively before and after PO spraying. The observation ability was assessed as scores from good (3) to slightly good (2) and poor (1), while the strength of peristalsis was assessed as scores from 3 (strong) to 2 (medium) and 1 (weak).