Douglas K. Rex, MD, MASGE reviewing Cronin O, et al. Endoscopy 2023 Sep 12.

There is a lack of data regarding the characteristics, prevalence, and endoscopic resection of large nonpedunculated colorectal polyps extending across an anastomosis. This study evaluated the safety and effectiveness of the combined use of piecemeal endoscopic mucosal resection and cold-forceps avulsion with adjuvant snare-tip soft coagulation for removing large anastomotic polyps.

Prateek Sharma, MD, FASGE reviewing Singh AP, et al. Gastrointest Endosc 2023 Aug 18.

The prevalence of GERD after peroral endoscopic myotomy (POEM) ranges from 13% to 58%. This variation is due to a lack of precise definitions and measurement methods for reflux, specifically, if pH monitoring results are used to define GERD. The aim of this study was to identify risk factors and determine the incidence of "true acid reflux" in patients with achalasia after POEM by manually analyzing pH tracings to characterize different acidification patterns.

Marietta Iacucci, MD, PhD, FASGE reviewing Schreiber S, et al. J Crohns Colitis 2023 Aug 16.

Although the STRIDE II consensus and guidelines strive to encompass clinical, biochemical, and endoscopic markers as treatment goals in ulcerative colitis, they may overlook some physical and psychological aspects that impact patients’ lives even during disease remission. In this study, a Delphi consensus panel aimed to expand on STRIDE II recommendations to define comprehensive disease control in ulcerative colitis.

Douglas K. Rex, MD, MASGE reviewing Jelsig AM, et al. Gastroenterology 2023 Aug 31.

Peutz-Jeghers syndrome (PJS) and juvenile polyposis syndrome (JPS) are hamartomatous polyposis syndromes associated with increased cancer risk. Researchers used the Danish national health registries, which systematically record health outcomes for the entire Danish population, to assess the risk of cancer and death in patients with these syndromes and compare them with matched controls.

Prateek Sharma, MD, FASGE reviewing Nabi Z, et al. Gastrointest Endosc 2023 Aug 17.

Peroral endoscopic myotomy (POEM) is a standard treatment option for patients with achalasia but is associated with a high incidence of GERD. Various techniques have been attempted to prevent GERD after POEM. In this randomized controlled trial, eligible patients with achalasia were randomly assigned to conventional or oblique fiber-sparing endoscopic myotomy to compare effectiveness at preventing reflux esophagitis.