Dr. Guha’s clinical practice focuses on the entire spectrum of general gastroenterology with special emphasis on screening and surveillance of colorectal cancer. Dr. Guha performs all general gastroenterology procedures including upper endoscopy, enteroscopy, colonoscopy, various hemostasis techniques and percutaneous endoscopic gastrostomy (PEG). In addition, Dr. Guha performs endoscopic mucosal resection (EMR) for large and flat polyps in colon and rectum.
Dr. Guha is active in several committees of American Gastroenterological Association (AGA) and American Society for Gastrointestinal Endoscopy (ASGE) including Center for GI Innovation and Technology (CGIT) and e-Learning committee, respectively.
Dr. Guha’s research comprises of both clinical and laboratory-based investigations. He has significant expertise in clinical outcomes research including meta-analysis and systematic reviews. Dr. Guha had received a NIH grant (R21) to investigate novel K-ras dependent signaling pathway in pancreatic cancer. Currently his research is focused on applications of artificial intelligence/machine learning in several GI topics including predictive analytics, assessing quality indicators in screening colonoscopy, operational efficiency in endoscopy unit and clinic, and image analysis in endoscopic procedures. Dr. Guha is the PI at UTHealth of U01 consortium grant “The Texas-Louisiana Alliance to Study Chronic Pancreatitis, Diabetes and Pancreatic Cancer” for the RFA for “Continuation of the Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Center (CPDPC)”. De. Guha and his team will be the TX partner in the TX-LA Alliance in the collaborative NIDDK/NCI Consortium. Our goal will be to boost recruitment and perform ancillary studies for PROCEED and DETECT cohorts. These clinical and translations studies will unravel the connections between chronic pancreatitis, diabetes and pancreatic cancer.