This study looked at issues of technical success and acceptance of panendoscopy with a colon capsule in 451 generally healthy adults aged 50 to 75 years. Patients received 5 mg of bisacodyl, 2 L of Moviprep (Norgine, Amsterdam, the Netherlands), and 2 L of water in a split dose. They also received a booster of 10 mg of metoclopramide and 0.5 L of oral sulfate solution, given as 0.25 L immediately after small bowel recognition and 0.25 L 3 hours later.
Cleansing of the entire GI tract was adequate in 52.8% of participants, but visualization was good for the stomach in 70% of patients and for the small bowel in 99.1%. For the colon, visualization was good or excellent in 77%, with insignificant bubbles in 75%.
The completion rate of the colon capsule was 51.9%, with 94.7% reaching the descending colon and 55.4% the rectum. The esophageal Z line was seen well in 44.8%.
Patients graded the experience at 7.8 on a scale of 1 to 10. Overall, 91% would consider a repeat colon capsule endoscopy, and only 6.6% would advise against it. The most burdensome part was bowel preparation, according to 89.2% of the patients.
Vuik FER, Moen S, Nieuwenburg SAV, Schreuders EH, Kuipers EJ, Spaander MCW. Applicability of colon capsule endoscopy as pan-endoscopy: from bowel preparation, transit, and rating times to completion rate and patient acceptance. Endosc Int Open